Causes for leaky gut syndrom

Why do we get leaky gut syndrom?

We all have some degree of leaky gut, as this barrier is not completely impenetrable (and isn’t supposed to be!). Some of us may have a genetic predisposition and may be more sensitive to changes in the digestive system, but our DNA is not the only one to blame.

Many factors can trigger intestinal hyperpermeability, here are the main ones:

  • Modern life may be the main driver of gut inflammation. modern food containing preservatives, additives, refined sugar, saturated fat aso. Food low in fiber and high in sugar and saturated fats, may initiate this process.

  • the imbalance of the intestinal flora (dysbiosis)

  • taking long-term medication such as antibiotics, anti-inflammatories, corticosteroids, etc.

  • the consumption of toxic substances: alcohol in large quantities, tobacco, food additives and preservatives, heavy metals, pesticides ...

  • an enzyme deficiency

  • Stress, reduces greatly the volume and quality of all digestive juices, stressed subjects also having insufficient chewing

  • intensive sport

  • Chronic inflammation/autoimmunity

  • viral intestinal infections (can modulate intestinal tight junction structure and function, and these effects may contribute to the development of chronic intestinal disorders.)

  • bacterial intestinal infections (can modulate intestinal tight junction structure and function, and these effects may contribute to the development of chronic intestinal disorders.)

  • fungal infections (Chronic candidiasis can modulate intestinal tight junction structure and function, and these effects may contribute to the development of chronic intestinal disorders.)

  • Parasites

  • a deficiency of IgA (immunoglobulin A) following frequent infections bacterial, viral, parasitic, mycotic ...

  • food intolerances including gluten intolerance.

  • chemotherapy and radiation damages, which destroys fast-growing cells such as cancer cells, but also those of the intestinal epithelium, but also the radiation centered on the intestine

It is already known that increased intestinal permeability plays a role in certain gastrointestinal conditions such as celiac disease, Crohn’s disease, and irritable bowel syndrome. Some studies show that leaky gut may be associated with other autoimmune diseases (lupus, type 1 diabetes, multiple sclerosis), chronic fatigue syndrome, fibromyalgia, arthritis, allergies, asthma, acne, obesity, and even mental illness.

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